BMJ Open 2013;3:e002091 doi:10.1136/bmjopen-2012-002091
Oral bisphosphonates are associated with increased risk of subtrochanteric and diaphyseal fractures in elderly women: a nested case–control study
A nested case–control study based on a general practice research database in Spain including 44 cases and 220 matched controls (mean age, 82 years), was published today in BMJ Open. The analysis was designed to evaluate the association between bisphosphonate use and the risk of atypical femoral fractures among women aged 65 or older. The investigators report that bisphosphonate use. was associated with an increased risk of subtrochanteric or diaphyseal fractures in elderly women in a low fracture risk population, with a higher risk among long-term bisphosphonate users.