TI Methods Speaker Series
WHEN: Wednesday, August 28th, 2019 from 12:00 noon to 1:00 PM
WHERE: Life Sciences Centre (LSC 1001), UBC Point Grey Campus. Remote attendance by videoconference is possible but you will need to register.
TITLE: It’s about Nothing: Dealing with Missing Data in Clinical Trials
SPEAKER: Joel Singer, PhD, Professor, School of Population and Public Health, University of British Columbia, Head, Data and Methodology Program, CIHR Canadian HIV Trials Network.
About the topic: Missing data, particularly on primary outcomes, presents a dilemma to researchers, not only because it may lead to lower than anticipated sample sizes and statistical power, but more seriously because missing data is often non-random and simply ignoring it can result in seriously biased comparisons. This talk will review the strategies that have been commonly used to cope with this problem, culminating in the more sophisticated models which impute data essentially using regression-like approaches. It is important to understand that even these more sophisticated approaches do make assumptions, and the use of statistical software does not obviate the need to think through the particular problem.
About the speaker: Dr. Singer has played an important role as the lead methodologist on numerous HIV clinical trials which have resulted in major publications in journals such as the New England Journal of Medicine, Lancet and JAMA. At the same time, he has collaborated with researchers in a number of clinical disciplines, including rheumatology, neonatology, nephrology, intensive care and emergency medicine to secure grants from major national and international funding agencies and to produce numerous publications in prominent journals. He has served on a number of national committees, including the CIHR Clinical Trials Review Panel, the acting chair of the CTN Data and Safety Monitoring Committee (DSMC), and is the current chair of the Ontario Clinical Oncology DSMC.
About the TI Methods Speaker Series: The TI Methods Speaker Series are offered free of charge and everyone is welcome, but space is limited, registered participants will be given priority. Remote attendance is possible by videoconference, you will receive the link after you register. Click here to view a list of all talks offered as part of the TI Methods Speaker Series.