...PPIs have not been endoscoped, so that “GERD” often refers to reflux or heartburn. Our previous reviews3-9 of randomized clinical trial (RCT) evidence on PPIs concluded: Over 8-12 weeks, PPIs...
...in the trial findings. Comparative trials of PPIs in adult patients with symptomatic GERD Based on 26 RCTs in 23,789 patients, esomeprazole was not significantly different from other PPIs for...
...that chronic PPI use without reassessment contributes to polypharmacy.15 What is the appropriate duration for PPIs? Proton pump inhibitors (PPIs) treat several different conditions including dyspepsia, gastroesophageal reflux disease (GERD),...
...British Columbians (9% of the population) filled at least one prescription for a PPI.1 Long-term use of PPIs in older adults We examined use of PPIs from 2009-2019 in people...