Rosiglitazone (Avandia®) Tolterodine (Detrol®) Bupropion (Wellbutrin SR®, Zyban®) Doxazosin (Cardura®) arm terminated in RCT Rosiglitazone (Avandia®) Approved indication: To lower blood glucose in patients with type 2 diabetes not controlled by diet and exercise alone: 1) as monotherapy or 2)...
Busy clinicians need distilled, concise, reliable, and readily available information about all types of therapy, especially drugs. 1) Distilled and concise, because most practitioners have little time to read original evidence or to perform their...
Orlistat (Xenical®) Raloxifene (Evista®) Spironolactone (Aldactone®) Orlistat (Xenical®) Approved indication: Management of obesity in patients with a body mass index (BMI) > 30 kg/m2 or a BMI > 27 kg/m2 in the presence of other cardiovascular risk factors (e.g....
The assessment of gabapentin (Neurontin) included in this Letter was based on potentially misleading information, as reported by the manufacturer. U.S. litigation in 2009-2010 has revealed that Neurontin’s off-label promotion, which over a relatively short...