Till 31 December 2019 there were 1,538 epidemiology preprints posted on bioRxiv. On January 5 2021, 844 (55%) of those were subsequently published as journal articles. We analysed 121 pairs of these preprints and their...
Clinicians are often interested in knowing how the accuracy of two or more diagnostic tests compare. For example, does CT have a higher sensitivity and specificity than ultrasound for diagnosing acute appendicitis? Comparative accuracy studies...
Soon after mirtazapine was licensed in Canada, a 2002 Therapeutics Letter concluded that it has “no proven efficacy or safety advantage over other antidepressant therapies”.1 Mirtazapine was approved for symptomatic relief of depressive illness and...
Carolina Moriello, MSc, J. Michael Paterson, MSc, Pauline Reynier, MSc, Matthew Dahl, BSc, Wusiman Aibibula, MD PhD, Anat Fisher, MD PhD, John-Michael Gamble, BSc(Pharm) PhD, I fan Kuo, PharmD MSc, Paul E. Ronksley, PhD, Brandace...