Soon after mirtazapine was licensed in Canada, a 2002 Therapeutics Letter concluded that it has “no proven efficacy or safety advantage over other antidepressant therapies”.1 Mirtazapine was approved for symptomatic relief of depressive illness and...
Carolina Moriello, MSc, J. Michael Paterson, MSc, Pauline Reynier, MSc, Matthew Dahl, BSc, Wusiman Aibibula, MD PhD, Anat Fisher, MD PhD, John-Michael Gamble, BSc(Pharm) PhD, I fan Kuo, PharmD MSc, Paul E. Ronksley, PhD, Brandace...
In this presentation, Dr. Till Bruckner provided examples of how hidden clinical trial results undermine clinical practice and harm patients, and presented concrete examples of how the problem can be fixed in practice. Some regulators,...
Ben-Eltriki M, Cassels A, Erviti J, Wright JM. Why we need a single independent international hypertension clinical practice guideline. Hypertens Res (2021). DOI: 10.1038/s41440-021-00666-6 Hypertension guidelines should be evidence-based and follow the principles of evidence-based medicine...