Statins and a Patient’s Perspective on Informed Decision-making Occasionally people read our Therapeutics Letters and contact us to share their experiences. These anecdotes are not systematically-reviewed evidence, but they sometimes give us insight to the dynamics...
A study published recently in PLOS One finds that cancer is increased with cumulative exposure to angiotensin-receptor blockers (ARBs). The authors carried out a meta-regression analysis, including 15 randomized clinical trials, zeroing in on cumulative exposure...
In our continued examination of drug safety warnings, researchers with UBC's Therapeutics Initiative, and others found that warnings about heart risks associated with the antihistamine drug hydroxyzine led to reduced prescribing in the UK but...
In July 2021 we published a Therapeutics Letter on tramadol and advised our readers that "Health Canada has announced that it will add tramadol to Schedule I of the Controlled Drugs and Substances Act and...