Dr. Jessica Otte: We Need To Talk About Tramadol
Dr. Jessica Otte, MD, CCFP gave this presentation on October 17th, 2020 at the "Bringing Best Evidence to Clinicians" virtual conference. Dr. Otte is a family physician in Nanaimo, BC. She has always been passionate about helping patients find the right health care according to the evidence and their needs and values, and she practices this daily with a focus on care of the elderly and palliative … [Read more...]
[128] Drug Safety Advisories: A need for international coordination
Vanessa Young of Oakville, Ontario died suddenly on March 19, 2000 at age 15. She was taking cisapride, a drug prescribed to “enhance stomach emptying” of whose link to fatal cardiac dysrhythmias the US FDA warned American doctors two months earlier.Health Canada delayed its own alert until after Vanessa’s sudden cardiac arrest at home.1 Her father Terence Young became the Conservative MP for … [Read more...]
[127] Audit and Feedback: Personal Prescribing Portrait
Primary care prescribers who treat a wide variety of conditions in community-dwelling patients require broad prescribing knowledge.1,2 The number of existing drug options and new drugs available each year has created a challenging work environment. There is a corresponding need to find innovative methods to help community-based physicians monitor and evaluate the appropriateness of their … [Read more...]
[Jan 13] TI Best Evidence Webinar: Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies
TI Best Evidence Webinar TITLE: Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies ABOUT THE TOPIC: Can a dramatic reduction in the incidence of childhood asthma be explained by falling antibiotic use in infancy? We present data from population, prospective cohort and microbiota studies that … [Read more...]
A Safety Net With Many Holes: Oseltamivir for Influenza Prophylaxis
Dr. Aaron Tejani, PharmD gave this presentation on October 17th, 2020 at the "Bringing Best Evidence to Clinicians" virtual conference. Dr. Tejani is a clinical assistant professor with the Faculty of Pharmaceutical Sciences (University of British Columbia), Medication use evaluation pharmacist with Lower Mainland Pharmacy Services (Vancouver, BC) and co-chair of the Education Working Group, UBC … [Read more...]
Do proton pump inhibitors increase mortality? A systematic review and in‐depth analysis of the evidence
Pharmacol Res Perspect. 2020; 8:e651. Ben‐Eltriki, M, Green, CJ, Maclure, M, Musini, V, Bassett, KL, Wright, JM Abstract: Proton pump inhibitors (PPIs) were primarily approved for short‐term use (2 to 8 weeks). However, PPI use continues to expand. Widely believed to be safe, we reviewed emerging evidence on increased mortality with PPI long‐term use. Our 2016 systematic PPI drug class … [Read more...]
Effectiveness and Safety among Direct Oral Anticoagulants in Non Valvular Atrial Fibrillation: A Multi‐Database Cohort Study with Meta‐Analysis
British Journal of Clinical Pharmacology, November 2020 Madeleine Durand, Mireille E. Schnitzer, Menglan Pang, Greg Carney, Sherif Eltonsy, Kristian B. Filion, Anat Fisher, Min Jun, I. fan Kuo, Alexis Matteau, J. Michael Paterson, Jacqueline Quail, Christel Renoux for the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators Abstract Background: There are conflicting … [Read more...]
[Dec 9] TI Best Evidence Webinar: Your Results Will Vary: Knowing the imprecision of medical measurements will make you a much better clinician
TI Best Evidence Webinar This webinar has already taken place. Scroll down to view the video recording. Click the Download button above or click here to download the handout. WHEN: Wednesday, December 9th, 2020 from 12:00 to 1:00 PM Pacific Time [click here to convert to your local time] WHERE: Offered online using Zoom. TITLE: Your Results Will Vary: Knowing the imprecision of … [Read more...]
[126] Serious harms with long-term PPI use in older adults
Proton pump inhibitors (PPIs) were introduced in 1988. Health Canada, professional, and academic groups all agree that they should be prescribed at the lowest dose and for the shortest duration appropriate to the condition treated. However, PPI use continues to expand. Between 2000 and 2018 BC’s population grew by 20%, but use of PPIs increased by 257%. In 2018, 442,559 British Columbians (9% of … [Read more...]
[Nov 25] TI Methods Speaker Series: Communicating the results of a systematic review in simple statements
TI Methods Speaker Series The TI Methods Speaker Series are offered free of charge and everyone is welcome. The event is held at noon on the last Wednesday of each month and used to take place in Rudy North Lecture Theatre (CBH 101) in the Centre for Brain Health, UBC Point Grey Campus. During the COVID-19 pandemic, while physical distancing measures are in effect, the TI Methods Speaker Series … [Read more...]
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