[128] Drug Safety Advisories: A need for international coordination
Vanessa Young of Oakville, Ontario died suddenly on March 19, 2000 at age 15. She was taking cisapride, a drug prescribed to “enhance stomach emptying” of whose link to fatal cardiac dysrhythmias the US FDA warned American doctors two months earlier.Health Canada delayed its own alert until after Vanessa’s sudden cardiac arrest at home.1 Her father Terence Young became the Conservative MP for … [Read more...]
Tofacitinib Persistence in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study
Editor's Pick: The Journal of Rheumatology, January 2021, 48(1):16-24. Anat Fisher, Marie Hudson, Robert W. Platt and Colin R. Dormuth for the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators Abstract Objective: To compare medication persistence of tofacitinib with persistence of injectable biological disease-modifying antirheumatic drugs (bDMARD) in … [Read more...]
[127] Audit and Feedback: Personal Prescribing Portrait
Primary care prescribers who treat a wide variety of conditions in community-dwelling patients require broad prescribing knowledge.1,2 The number of existing drug options and new drugs available each year has created a challenging work environment. There is a corresponding need to find innovative methods to help community-based physicians monitor and evaluate the appropriateness of their … [Read more...]
[Mar 31] TI Methods Speaker Series: The development of a risk of bias tool for network meta-analysis
TI Methods Speaker Series The TI Methods Speaker Series are offered free of charge and everyone is welcome. The event is held at noon on the last Wednesday of each month and used to take place in Rudy North Lecture Theatre (CBH 101) in the Centre for Brain Health, UBC Point Grey Campus. During the COVID-19 pandemic, while physical distancing measures are in effect, the TI Methods Speaker Series … [Read more...]
[Mar 17] Therapeutics Initiative Best Evidence Webinar: Withdrawal of antihypertensive drugs in older people
TI Best Evidence Webinar TITLE: Withdrawal of antihypertensive drugs in older people PRESENTER: Dr. Emily Reeve is a pharmacist and Senior Research Fellow in the Quality Use of Medicines and Pharmacy Research Centre, UniSA Clinical and Health Sciences, at the University of South Australia. Dr Reeve is currently supported by an Australian National Health and Medical Research Council … [Read more...]
[Mar 10] Therapeutics Initiative Virtual Workshop – Using Evidence in Shared Decision Making: A Case-based, Critical Appraisal Approach for Busy Clinicians
An interactive session where we analyze a recent study and interpret and apply the findings to a clinical case This workshop has already taken place. Scroll down to view a video recording of the event. PRESENTED BY: Rita McCracken, MD, CCFP Cait O'Sullivan, PharmD Jessica Otte, MD, CCFP Aaron M. Tejani, PharmD DATE: Wednesday, March 10th, 2021 TIME: 12:00 … [Read more...]
[Feb 24] TI Methods Speaker Series: Should research in predatory journals be included in systematic reviews?
TI Methods Speaker Series The TI Methods Speaker Series are offered free of charge and everyone is welcome. The event is held at noon on the last Wednesday of each month and used to take place in Rudy North Lecture Theatre (CBH 101) in the Centre for Brain Health, UBC Point Grey Campus. During the COVID-19 pandemic, while physical distancing measures are in effect, the TI Methods Speaker Series … [Read more...]
[Feb 10] Therapeutics Initiative Best Evidence Webinar: Sex and Post-SSRI Evidence-based Medicine Dysfunction
TI Best Evidence Webinar TITLE: Sex and Post-SSRI Evidence-based Medicine Dysfunction PRESENTER: A professor of Psychiatry in the Department of Family Medicine at McMaster University, Dr. David Healy studied medicine in Dublin, and at Cambridge University. He is a former Secretary of the British Association for Psychopharmacology, and has authored more than 200 peer-reviewed … [Read more...]
[Jan 27] TI Methods Speaker Series: On the difficulties in determining the lethality of COVID-19 and the various ways in which Bayesian methods can help
TI Methods Speaker Series The TI Methods Speaker Series are offered free of charge and everyone is welcome. The event is held at noon on the last Wednesday of each month and used to take place in Rudy North Lecture Theatre (CBH 101) in the Centre for Brain Health, UBC Point Grey Campus. During the COVID-19 pandemic, while physical distancing measures are in effect, the TI Methods Speaker Series … [Read more...]
[Jan 13] TI Best Evidence Webinar: Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies
TI Best Evidence Webinar TITLE: Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies ABOUT THE TOPIC: Can a dramatic reduction in the incidence of childhood asthma be explained by falling antibiotic use in infancy? We present data from population, prospective cohort and microbiota studies that … [Read more...]
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