Colin R. Dormuth, Anat Fisher, Marie Hudson, Peter C. Austin, Pierre Ernst, Lauren Bresee, Dan Chateau, Hala Tamim, J. Michael Paterson, Jean Philippe Lafrance, Regina M. Taylor-Gjevre, Robert W. Platt, Canadian Network for Observational Drug Effect Studies (CNODES) Investigators. Impact of using concomitant conventional DMARDs on adherence to biologic DMARD treatment in rheumatoid arthritis: … [Read more...]
PharmacoEpidemiology Group (PEG) conducts research in the areas prescription drug utilization, epidemiological research methods, evaluation of drug policy and educational interventions, and drug safety and effectiveness. Selected journal articles and reports co-authored by PEG members are listed below.
Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study
Lix LM, Sobhan S, St-Jean A, Daigle J-M, Fisher A, et al. Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study. BMC Health Serv Res 21, 758 (2021). https://doi.org/10.1186/s12913-021-06762-0 Abstract Background Cardiovascular death is a common outcome in population-based studies about new healthcare … [Read more...]
Off-label postpartum use of domperidone in Canada: a multidatabase cohort study
Carolina Moriello, MSc, J. Michael Paterson, MSc, Pauline Reynier, MSc, Matthew Dahl, BSc, Wusiman Aibibula, MD PhD, Anat Fisher, MD PhD, John-Michael Gamble, BSc(Pharm) PhD, I fan Kuo, PharmD MSc, Paul E. Ronksley, PhD, Brandace Winquist, PhD, Kristian B. Filion, PhD for the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators. Off-label postpartum use of domperidone in … [Read more...]
Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort
Colin R. Dormuth, Brandace Winquist, Anat Fisher, et al JAMA Netw Open. 2021;4(4):e215329. doi:10.1001/jamanetworkopen.2021.5329 Key Points Question: What is the association between ondansetron exposure during pregnancy and the risk of adverse fetal outcomes? Findings: In this meta-analysis of cohort studies of 456 963 pregnancies in 3 countries, treatment with ondansetron was not … [Read more...]
Tofacitinib Persistence in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study
Editor's Pick: The Journal of Rheumatology, January 2021, 48(1):16-24. Anat Fisher, Marie Hudson, Robert W. Platt and Colin R. Dormuth for the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators Abstract Objective: To compare medication persistence of tofacitinib with persistence of injectable biological disease-modifying antirheumatic drugs (bDMARD) in … [Read more...]
Effectiveness and Safety among Direct Oral Anticoagulants in Non Valvular Atrial Fibrillation: A Multi‐Database Cohort Study with Meta‐Analysis
British Journal of Clinical Pharmacology, November 2020 Madeleine Durand, Mireille E. Schnitzer, Menglan Pang, Greg Carney, Sherif Eltonsy, Kristian B. Filion, Anat Fisher, Min Jun, I. fan Kuo, Alexis Matteau, J. Michael Paterson, Jacqueline Quail, Christel Renoux for the Canadian Network for Observational Drug Effect Studies (CNODES) Investigators Abstract Background: There are conflicting … [Read more...]
Sodium–Glucose Cotransporter 2 Inhibitors and the Risk of Below-Knee Amputation: A Multicenter Observational Study
Diabetes Care Aug 2020, dc200267; DOI: 10.2337/dc20-0267 Oriana Hoi Yun Yu, Sophie Dell’Aniello, Baiju R. Shah, Vanessa C. Brunetti, Jean-Marc Daigle, MichaelFralick, Antonios Douros, Nianping Hu, Silvia Alessi-Severini, Anat Fisher, Shawn C. Bugden, Paul E.Ronksley, Kristian B. Filion, Pierre Ernst, Lisa M. Lix for the Canadian Network for Observational Drug Effect Studies (CNODES) … [Read more...]
Sodium glucose cotransporter 2 inhibitors and risk of major adverse cardiovascular events: multi-database retrospective cohort study
BMJ 2020; 370 DOI: https://doi.org/10.1136/bmj.m3342 (Published 23 September 2020) Kristian B Filion, Lisa M Lix, Oriana HY Yu, Sophie Dell’Aniello, Antonios Douros, Baiju R Shah, Audray St-Jean, Anat Fisher, Eric Tremblay, Shawn C Bugden, Silvia Alessi-Severini, Paul E Ronksley, Nianping Hu, Colin R Dormuth, Pierre Ernst, Samy Suissa, on behalf of the Canadian Network for Observational Drug … [Read more...]
Sodium–Glucose Cotransporter-2 Inhibitors and the Risk for Diabetic Ketoacidosis
Annals of Internal Medicine 2020 July 28. DOI: 10.7326/M20-0289 Antonios Douros, MD, PhD; Lisa M. Lix, PhD; Michael Fralick, MD, PhD; Sophie Dell’Aniello, MSc; Baiju R. Shah, MD, PhD; Paul E. Ronksley, PhD; Eric Tremblay, BPharm, MSc; Nianping Hu, PhD; Silvia Alessi-Severini, PhD; Anat Fisher, MD, PhD; Shawn C. Bugden, PharmD, MSc; Pierre Ernst, MD, MSc; and Kristian B. Filion, PhD; for the … [Read more...]
Rapid monitoring of health services utilization following a shift in coverage from brand name to biosimilar drugs in British Columbia—An interim report
Pharmacoepidemiol Drug Saf. 2020;1–8. First published: 28 May 2020. Fisher A, Kim JD, Dormuth CR Purpose: We explored changes in health services utilization associated with the Biosimilars Initiative introduced in British Columbia on May 27, 2019. To maintain drug coverage, the policy requires users of originator infliximab or etanercept to transition to biosimilar versions. We present a … [Read more...]
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