Therapeutics Letter
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This is a bi-monthly letter targeting identified problematic therapeutic issues (brief, simple, practical messages). The process involves a literature review and development of the message by different working groups of the Therapeutics Initiative. A draft of the letter is reviewed by specialists who are expert in the particular therapeutic area and members of the Scientific Information and Education Committee before the letter is disseminated. The Therapeutics Initiative is a member of the International Society of Drug Bulletins. |
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To view the letter in your browser please click on HTML or to download a printer friendly version of the letter please click on PDF.
| Issue | Title | HTML | |
|---|---|---|---|
| Issue 74, Apr - Jun 2009 |
Increasing use of newer antipsychotics in children: A cause for concern? | HTML | PDF (123 KB) |
| Issue 73, Jan - Mar 2009 |
Atomoxetine for ADHD in children and adolescents | HTML | PDF (172 KB) |
| Issue 72, Nov - Dec 2008 |
Prescription drug costs: BC versus Canada | HTML | PDF (148 KB) |
| Issue 71, Sep - Oct 2008 |
Treatment of elevated blood pressure in the very elderly: Less is better | HTML | PDF (120 KB) |
| Issue 70, Jun - Aug 2008 |
Clinical Pearls from the most popular Cochrane reviews in 2007 | HTML | PDF (116 KB) |
| Issue 69, Mar - May 2008 |
What is the evidence for using CNS stimulants to treat ADHD in children? | HTML | PDF (119 KB) |
| Issue 68, Jan - Feb 2008 |
Glycemic Targets in Type 2 Diabetes | HTML | PDF (276 KB) |
| Issue 67, Nov - Dec 2007 |
Evaluating the Media as a source of Drug Therapy Information | HTML | PDF (276 KB) |
| Issue 66, Sep - Oct 2007 |
Is newer better? New drugs for treatment of overactive bladder | HTML | PDF (276 KB) |
| Issue 65, Jul - Aug 2007 |
Clinical implications of recent key therapeutic trials | HTML | PDF (212 KB) |
| Issue 64, May - Jun 2007 |
Your opinions of the Therapeutics Letter: The 2006 Survey | HTML | PDF (156 KB) |
| Issue 63, Mar - Apr 2007 |
Using Framingham for primary prevention cardiovascular risk assessment | HTML | PDF (156 KB) |
| Issue 62, Jan - Feb 2007 |
Mild Hypertension - An approach to using evidence in the decision making process | HTML | PDF (124 KB) |
| Issue 61, Oct - Dec 2006 |
What is the Common Drug Review? | HTML | PDF (352 KB) |
| Issue 60, Aug - Sep 2006 |
Clinical Pearls from Prescrire | HTML | PDF (132 KB) |
| Issue 59 Apr - Jul 2006 |
Increasing Drug Costs: Are we getting good value? | HTML | PDF (124 KB) |
| Issue 58, Jan - Mar 2006 |
Benign Prostatic Hypertrophy: An update on drug therapy. | HTML | PDF (132 KB) |
| Issue 57, Sep - Dec 2005 |
Drugs for Overactive Bladder Symptoms | HTML | PDF (116 KB) |
| Issue 56, Apr - Aug 2005 |
Drugs for Alzheimer's Disease | HTML | PDF (224 KB) |
| Issue 55, Jan - Mar 2005 |
Clinical Pearls from The Cochrane Library | HTML | PDF (108 KB) |
| Issue 54, Nov - Dec 2004 |
Use of Benzodiazepines in BC: Is it consistent with recommendations? | HTML | PDF (116 KB) |
| Issue 53, Jul - Oct 2004 |
Rofecoxib (Vioxx®) withdrawal generates uncertainty about “COX-2s”: Do product monographs adequately inform? | HTML | PDF (104 KB) |
| Issue 52, Apr - Jun 2004 |
Antidepressant Medications in Children and Adolescents | HTML | PDF (112 KB) |
| Issue 51, Jan - Mar 2004 |
New Drugs VIII Telithromycin (Ketek) Ezetimibe (Ezetrol) Topical Pimecrolimus (Elidel) and Tacrolimus (Protopic) |
HTML | PDF (168 KB) |
| Issue 50, Oct - Dec 2003 |
Can blood pressure be lowered by a change in diet? Evidence from the DASH trials | HTML | PDF (168 KB) |
| Issue 49, Jul - Sep 2003 |
Statins' benefit for secondary prevention confirmed. What is the optimal dosing strategy? | HTML | PDF (88 KB) |
| Issue 48, Apr - Jun 2003 |
Do Statins have a Role in Primary Prevention? | HTML | PDF (88 KB) |
| Issue 47, Jan - Mar 2003 |
The Answer: Thiazides First-line for Hypertension | HTML | PDF (80 KB) |
| Issue 46, Oct - Dec 2002 |
Menopausal Combined Hormone Therapy Update | HTML | PDF (88 KB) |
| Issue 45, Jun - Sep 2002 |
Do Single Stereoisomer Drugs Provide Value? | HTML | PDF (88 KB) |
| Issue 44, Feb - May 2002 |
New Drugs VII Mirtazapine (Remeron®) Salmon-Calcitonin Nasal Spray (Miacalcin®) Gatifloxacin (Tequin®)and Moxifloxacin (Avelox®) |
HTML | PDF (80 KB) |
| Issue 43, Nov 2001 - Jan 2002 |
COX-2 inhibitors update: Do journal publications tell the full story? | HTML | PDF (116 KB) |
| Issue 42, Aug - Oct 2001 |
Serious Adverse Event Analysis: Lipid-Lowering Therapy Revisited | HTML | PDF (128 KB) |
| Issue 41, May - Jul 2000 |
Asymptomatic Bacteriuria in Pregnancy: Rapid answers using the Cochrane Library | HTML | PDF (104 KB) |
| Issue 40, Mar - Apr 2001 |
Direct to Consumer Advertising: Finasteride for male pattern hair loss | HTML | PDF (100 KB) |
| Issue 39, Jan - Feb 2001 |
Selective COX-2 inhibitors: Are they safer NSAIDs? | HTML | PDF (64 KB) |
| Issue 38, Nov - Dec 2000 |
Prevention and Treatment of Influenza A and B | HTML | PDF (104 KB) |
| Issue 37, Sep - Oct 2000 |
Antiplatelet Chemoprevention of Occlusive Vascular Events and Death | HTML | PDF (132 KB) |
| Issue 36, Jul - Aug 2000 |
New Drugs VI Rosiglitazone (Avandia®) Tolterodine (Detrol®) Bupropion (Wellbutrin SR®, Zyban®) Doxazosin (Cardura®) arm terminated in RCT |
HTML | PDF (100 KB) |
| Issue 35, May - Jun 2000 |
Sources of Drug Therapy Information | HTML | PDF (100 KB) |
| Issue 34, Mar - Apr 2000 |
New Drugs V Orlistat (Xenical®) Raloxifene (Evista®) Spironolactone (Aldactone®) |
HTML | PDF (96 KB) |
| Issue 33, Jan - Feb 2000 |
Treatment of Pain in the Older Patient | HTML | PDF (172 KB) |
| Issue 32, Oct - Nov 1999 |
Management of Erectile Dysfunction | HTML | PDF (88 KB) |
| Issue 31, Aug - Sep 1999 |
Celecoxib (Celebrex®): Is it a Breakthrough Drug? | HTML | PDF (140 KB) |
| Issue 30, Jun - Jul 1999 |
Levels of Evidence for Clinical Decisions: Menopausal Hormone Therapy Revisited | HTML | PDF (104 KB) |
| Issue 29, Apr - May 1999 |
Leukotriene Antagonists: What is their Role in the Manament oof Asthma? | HTML | PDF (116 KB) |
| Issue 28, Jan - Mar 1999 |
Angiotensin II Receptor Blockers | HTML | PDF (108 KB) |
| Issue 27, Nov - Dec 1998 |
Review and Update 1998 Treatment of Hypertension Treatment of Type 2 Diabetes Lipid Lowering Therapy Olanzapine |
HTML | PDF (112 KB) |
| Issue 26, May - Jun 1998 |
New Drugs IV Donepezil (Aricept®) Levofloxacin (Levaquin®) Pantoprazole (Pantoloc®) Quetiapine (Seroquel®) |
HTML | PDF (108 KB) |
| Issue 25, Jun - Aug 1998 |
Herbal Medicines: An Evidence Based Look | HTML | PDF (120 KB) |
| Issue 24, Apr - May 1998 |
Lipid Lowering Therapy | HTML | PDF (140 KB) |
| Issue 23, Jan - Mar 1998 |
Management of Type 2 Diabetes | HTML | PDF (148 KB) |
| Issue 22, Nov - Dec 1997 |
Treatment of Acute Migraine Headaches | HTML | PDF (140 KB) |
| Issue 21, Sep - Oct 1997 |
Effective Clinical Tobacco Intervention | HTML | PDF (140 KB) |
| Issue 20, Jul - Aug 1997 |
New Drugs III: Alendronate (Fosamax®) Dorzolamide (Trusopt®) Acarbose (Prandase®) Olanzapine (Zyprexa®) |
HTML | PDF (120 KB) |
| Issue 19, May - Jun 1997 |
Medical Management of Benign Prostatic Hyperplasia | HTML | PDF (148 KB) |
| Issue 18, Feb -Apr 1997 |
Management of Anxiety Disorders in Primary Care | HTML | PDF (136 KB) |
| Issue 17, Jan 1997 |
New Drugs II Famciclovir (Famvir) Valacyclovir (Valtrex) Torsemide (Demadex) Etodolac (Ultradol) Naltrexone (Revia) |
HTML | PDF (116 KB) |
| Issue 16, Jan - Feb 1996 |
Review and Update 1996 H.pylori and Gastro-esophageal Reflux Treatment of Angina and Hypertension: Calcium Channel Blocker Controversy Changing concepts in the management of asthma Menopausal Hormone Therapy |
HTML | PDF (208 KB) |
| Issue 15, Aug - Oct 1996 |
Evidence Based Drug Therapy: What Do the Numbers Mean? | HTML | PDF (124 KB) |
| Issue 14, May - Jul 1996 |
Menopausal Hormone Therapy | HTML | PDF (144 KB) |
| Issue 13, Mar - Apr 1996 |
New Drugs I Losartan (Cozaar®) Lansoprazole (Prevacid®) Cefprozil (Cefzil®)F Zuclopenthixol (Clopixol®) |
HTML | PDF (116 KB) |
| Issue 12, Jan - Feb 1996 |
Changing Concepts in the Management of Asthma | HTML | PDF (136 KB) |
| Issue 11, Nov - Dec 1995 |
To Sleep or Not to Sleep: These Are Your Questions | HTML | PDF (108 KB) |
| Issue 10, Oct 1995 |
Dose Titration: Minimize to Maximize | HTML | PDF (80 KB) |
| Issue 9, Sep 1995 |
Review and Update Our position on Reference Based Pricing Therapeutics Initiative process H2-blockers H. pylori Gastroesophageal Reflux NSAIDs for Osteoarthritis Anti-Infective Guidelines Nitrates for Stable Angina Treatment of Hypertension |
HTML | PDF (132 KB) |
| Issue 8, Jul - Aug 1995 |
Drugs of Choice in the Treatment of Hypertension, Part 2 | HTML | PDF (344 KB) |
| Issue 7, Jun 1995 |
Drugs of Choice in the Treatment of Hypertension, Part 1 | HTML | PDF (108 KB) |
| Issue 6, May 1995 |
Medical Management of Ischemic Heart Disease: the Optimal Use of Nitrates | HTML | PDF (96 KB) |
| Issue 5, Mar 1995 |
Anti-infective Guidelines for Community-Acquired Infections | HTML | PDF (96 KB) |
| Issue 4, Feb 1995 |
Should We Be Using NSAIDs for the Treatment of Osteoarthritis and "Rheumatism"? | HTML | PDF (120 KB) |
| Issue 3, Dec 1994 |
Treatment of Gastroesophageal Reflux Disease (GERD) | HTML | PDF (124 KB) |
| Issue 2, Nov 1994 |
Definitive Treatment of Peptic Ulcer Disease by Eradication of H. Pylori | HTML | PDF (116 KB) |
| Issue 1, Oct 1994 |
Treatment of Non-Ulcer Dyspepsia in Adults: Common Questions about H2-blockers | HTML | PDF (232 KB) |
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