Most Therapeutics Letters analyze evidence to draw conclusions about average drug effects in defined groups of people. This Letter takes a clinical pharmacological approach to review how individuals may be harmed by dopamine (DA) receptor...
A multi-country retrospective cohort study Authors: Anat Fisher, J. Michael Paterson, Brandace Winquist, Fangyun Wu, Pauline Reynier, Samy Suissa, Matthew Dahl, Zhihai Ma, Xinya Lu, Jianguo Zhang, Colette B. Raymond, Kristian B. Filion, Robert W. Platt, Carolina Moriello, Colin R. Dormuth, for the Canadian Network for Observational Drug Effect Studies...
Case vignette: A 70-year-old woman is diagnosed with COPD, obstructive sleep apnea, left ventricular dysfunction with outflow obstruction, hypertension, prior pulmonary embolism, insomnia, anxiety, depression, mild cognitive impairment, and unexplained laryngitis. She takes 14 prescription drugs...
In a unique international study, researchers found that drug safety advisories issued by regulators regularly led to reductions in prescribing of those treatments. Published in BMJ Quality & Safety, this study measured the impact on...