An individual Portrait on prescribing the non-opioid pain medications gabapentin, pregabalin, and cyclobenzaprine was sent to approximately 6000 family doctors in BC. Physicians have been randomly divided into two groups to receive the Portrait at...
Some prescribers “titrate” patients to high “target” doses of cyclobenzaprine, duloxetine, gabapentin or pregabalin; and some guidelines advocate progressive dose increases.1-3 Whether intended to minimize adverse effects, or to improve pain relief, this approach is...
Analgesia once seemed a relatively straightforward aspect of medicine. Recommendations in textbooks and guidelines were definitive, albeit heavily conflicted. Even recent guidelines encourage dose titration, based on an implicit, if unsupported, notion that more is likely...
Chronic pain (at times presumed to be “neuropathic” in origin) is a common problem in clinical practice. It is now well recognized that the results of drug treatment are more often disappointing than not.1 Despite this, from 2005-2014 the number...