An individual Portrait on prescribing the non-opioid pain medications gabapentin, pregabalin, and cyclobenzaprine was sent to approximately 6000 family doctors in BC. Physicians have been randomly divided into two groups to receive the Portrait at...
Some prescribers “titrate” patients to high “target” doses of cyclobenzaprine, duloxetine, gabapentin or pregabalin; and some guidelines advocate progressive dose increases.1-3 Whether intended to minimize adverse effects, or to improve pain relief, this approach is...
Cyclobenzaprine is a tricyclic molecule discovered in 1956 that is structurally related to amitriptyline and imipramine. Evaluated first as a possible tranquilizer, it was noted to have atropine-like properties in animals.1 In Canada, Merck Frosst...