In this presentation, Tom Stanley shows how excess statistical significance (ESS) can improve the credibility of research synthesis. This generalizes on the notion of an excess of statistical significance by Ioannidis & Trikalinos’ (2007) that...
Anat Fisher, Jason D. Kim, Colin R. Dormuth CMAJ Open February 15, 2022 10 (1) E109-E118; DOI: 10.9778/cmajo.20200319 Abstract Background: In 2019, British Columbia’s public drug plan, PharmaCare, was the first in Canada to implement a nonmedical switching...
In a unique international study, researchers found that drug safety advisories issued by regulators regularly led to reductions in prescribing of those treatments. Published in BMJ Quality & Safety, this study measured the impact on...
Click on the 'Download' button to access the full report. Below you can read the executive summary. Executive Summary Background Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by airway inflammation and airflow limitation that...