Anticholinergic drugs, prescribed for a variety of clinical conditions, are amongst the most frequently used prescription drugs in BC (Table 1). Also referred to as “antimuscarinics,” such drugs specifically block muscarinic receptors for acetylcholine (ACh).1...
Antidepressant drugs are associated with drug tolerance, dependence and a discontinuation syndrome similar to other drug classes such as the opiates and benzodiazepines. The effects of stopping any antidepressant should be more precisely termed “withdrawal...
The first PPI was approved in Canada in 1988. Pronounced and durable reduction of stomach acid production made omeprazole a “blockbuster drug”, spawning multiple imitators. Eventually this included (as patent extensions) the single enantiomers esomeprazole...
Drug Assessment Working Group Systematic Review Report Efficacy and safety of adjuvanted herpes zoster subunit vaccine October 2018 Background Herpes zoster (HZ) or “shingles” infection occurs through the reactivation of latent varicella zoster virus (VZV) in the sensory ganglia....